What is the effect of HIV on the body?

The effect of HIV (Human Immunodeficiency Virus) on the body primarily involves the weakening of the immune system, which can ultimately lead to Acquired Immunodeficiency Syndrome (AIDS). HIV specifically targets and destroys CD4 cells, which are crucial components of the immune system. As the number of these cells declines, the body's ability to fight off infections and certain cancers diminishes significantly. This progression is why individuals with HIV are at a greater risk for opportunistic infections and other health complications.

As the virus progresses, without appropriate treatment, it can transition into AIDS, the most severe phase of HIV infection. In this stage, the immune system is severely compromised, making it possible for infections to become life-threatening. Hence, option C accurately reflects the primary and devastating impact of HIV on the body's immune response.